ENTEXS MIDI + RMD - Inline Remediation Extraction System

The New Era of Pharmaceutical-Grade Cannabis Oil Extraction

The cannabis oil extraction industry is undergoing a profound transformation, driven by increasingly stringent regulations, higher quality requirements, and the need to operate with true industrial efficiency. Producers seeking to compete in regulated markets—particularly in the United States—must comply not only with federal THC limits, but also with pharmaceutical standards for purity, traceability, process safety, and final product consistency.

Recent regulatory updates in the United States, together with more rigorous oversight by federal and state agencies, have raised the technical threshold required for extraction systems. Today, achieving yield alone is no longer sufficient: the market demands ultra-high-purity, THC-free extracts produced through closed, automated, and validated processes that reduce operational risk and the costs associated with labor-intensive operations.

In this context, ENTEXS develops and implements technologies aligned with the real needs of the modern industry: next-generation systems that are fully automated and optimized to maximize yield, profitability, and regulatory compliance. Our solutions enable end-to-end processing—from biomass to crude oil or final distillate—integrating extraction, THC remediation, and refinement within a single industrial platform.

From Biomass to Pharma-Grade Oil: The Automated, Closed-Loop Extraction Solution

The ENTEXS MIDI + RMD is a turnkey industrial extraction platform purpose-built for processors targeting pharmaceutical, nutraceutical, and tightly regulated consumer markets. Delivering an end-to-end workflow from biomass input to full-spectrum crude and/or distillate, the system combines closed-cycle extraction, inline THC remediation, multistage filtration, closed-loop solvent recovery, and two-step distillation into a single automated, validated production line. With a processing capacity of up to 5,000 lb per day, MIDI + RMD reduces operational complexity while improving yield consistency, product purity, and regulatory readiness.

Market context and compliance priorities

Processors moving into federally regulated or GMP environments face stricter demands for traceability, product purity, repeatability, and operator safety. Traditional, fragmented workflows (manual transfers, open pours, standalone rotovaps, and vacuum ovens) introduce variability, contamination risk, and documentation challenges. ENTEXS addresses these pain points by integrating critical unit operations into a closed, controlled, and auditable system designed to support SOPs, validation, and GMP compliance.

100L / 5000 lbs per day

entexsinline rmd

System overview, how MIDI + RMD delivers value

✅ Closed high-capacity centrifuge extraction using ultra-cold ethanol: Closed extraction cycles using ultra-cold ethanol capture cannabinoids and preserve terpene profiles with no need for pre-winterization, reducing processing steps and preserving product integrity.

✅ Inline remediation and multistage filtration: Particle and color remediation occur across multiple filtration stages. Interstage pressure sensors and sight glasses provide real-time quality feedback for consistent, validated output.

✅ Closed-loop solvent recovery with vacuum desolventization and decarboxylation: Continuous solvent recovery and controlled desolventization/decarboxylation cycles enable the production of full-spectrum crude under vacuum and reduced temperatures—eliminating the need for external rotary evaporators or vacuum ovens for final processing.
✅ Two-step (double-pass) distillation: The two-step distillation sequence separates terpenes in the first pass and conducts final distillation in the second pass to produce high-purity distillate suitable for pharmaceutical and other regulated applications.

✅ Full automation and process safety: Push-button routines, recipe management, and adjustable parameters minimize labor requirements and ensure repeatability. Integrated heated lines and pumps eliminate open pours and the use of ad-hoc external heat sources.

✅ Industrial throughput: Designed for up to 5,000 lb/day throughput with modular scalability for larger operations.

The ENTEXS MIDI + RMD represents the next generation of industrial extraction technology. By combining high throughput with pharmaceutical-grade precision, it provides a turnkey solution for manufacturers ready to scale. Whether you are aiming for full-spectrum crude or high-purity distillate, this system delivers the reliability and compliance required to lead in today’s competitive market.

Request a Consultation

Fill out the form below and connect with one of our specialists. Whether you’re looking for expert guidance on extraction, remediation, or post-processing equipment—or simply have questions—we’re here to help you find the ideal solution for your specific needs. Let’s make your project a success!!